N=8 Rats, N=1 Tuesday

Extrapolating a small-cohort rodent study directly into your Monday morning protocol like a one-man IRB.

Filed under SLU-PP-332 ·Dihexa ·Humanin · #stack-life ·#cope ·#n-of-1

Active Compounds

SLU-PP-332 · Exercise Mimetic

A synthetic exercise mimetic that activates estrogen-related receptors (ERRs) to replicate the molecular effects of aerobic exercise — increasing endurance, fat oxidation, and mitochondrial function without physical activity.

Dihexa · Angiotensin Analog

A potent angiotensin IV analog studied for cognitive enhancement. Its Dihexa-derived prodrug fosgonimeton failed its Phase 2/3 Alzheimer's trial (LIFT-AD, 2024), and the foundational 2014 HGF/c-Met mechanism paper was retracted in 2025 — material context that reshapes how the preclinical literature should be read.

Humanin · Mitochondrial-Derived Peptide

A mitochondria-derived peptide with cytoprotective properties, studied for neuroprotection, metabolic regulation, and anti-aging effects.

RX: SLU-PP-332 · Dihexa · Humanin
Dosage: 8 rats per arm
Half-life: until peer review
Source: manual
Tags: stack-life , cope , n-of-1
Stamped: 2026-06-20 · Cycle 025
Lot #: LOT-20260620T21:35:17.329Z